"Losek CI": faatonuga mo le faaaogaina. "Losek CI": togafitiga, iloiloga, faailoga, contraindications

Pe e te iloa o lena, mai le mea e faia e lenei fualaau faasaina o le "Losek CI"? Faatonuga mo le faaaogaina, e pei foi o le a faamatalaina faailoga o le fualaau faasaina i lenei mataupu. I le faaopoopo atu, tatou te a taʻu atu e le tele o le tau, na fai mai o lona uiga, afai sa ia te ia so o se analogues ma contraindications, o le a itu aafiaga tupu pe a mavae pulega, ma isi.

Tuufaatasiga, afifiina ma le ituaiga o fualaau faasaina

O le a le fofo "Losek CI"? Faatonuga mo le faaaogaina e logoina i tatou e faapea e na o le maua o lenei fualaau faasaina i se faiga laupapa. O le medicament elemene malolosi galue omeprazole (10, 40 po o le 20 mg). Foi, o mea laupapa e aofia ai ma ausilali: glyceryl monostearate, MCC, methylcellulose hydroxypropyl, hydroxypropyl cellulose, stearate magnesium, suka, acid methacrylic, talc, paraffin, citrate triethyl, polyethylene glycol, karaponi titanium, polysorbate, uʻamea oxide, crosslinked polyvinylpyrrolidone ma sodium fumarate stearyl .

e mafai ona i fagu o 14 medicament faatauina mai, 7 po o le 28 papa (10, 40 po o le 20 mg) na tuu i se pusa pepa malo.

pharmacodynamics

E faapefea e le fualaau faasaina "Losek CI"? Faatonuga mo le setete faaaogāina lea toaga fualaau faasaina o se inhibitor o H + -K + -ATPase. Lē gata i lea, e faatatau i sui aneti-papala. O lona sui sooupu toaga o se faavae vaivai. E taulai i le siosiomaga acid o le sela parietal o le mucosa gastric, faagaoioia ma inhibiting le pamu proton.

Taunuuga o le omeprazole i le faagasologa o le faamatalaina o inumaga-faalagolago. A medicament mafai ona tuuina inhibition maualuga lelei o basal ma stimulated secretion acid e tusa lava po o le vaega stimulatory.

Taunuuga i luga o le secretion o sua gastric

Faatasi ai ma le medicament tuufofoga i aso taitasi "Losek CI", o le tau o lea o le a tuuina atu teisi, maua inhibition lelei ma le vave o le po ma le ao secretion o acid hydrochloric. O le aafiaga togafitiga sili ua matauina totonu o le 4 aso o togafitiga. mafua ai tagata ma papala 12 mg papala 20 duodenal o le fualaau faasaina a faaitiitia mausali i le 24-itula acidity gastric o le itiiti ifo i le 80%. E tatau foi ona taʻua o lenei inumaga o medicament e mafai ona ia faatumauina le auala i tulaga acidity intragastric o TA> 3. O lenei aafiaga umi 17 itula.

Aafiaga i pylori Helicobacter

E faapefea lelei galue e faasaga i le vailaau siama fai mai "Losek CI"? O Tulafono Faatonutonu ua faapipii atu i le fualaau faasaina, o loo faapea mai omeprazole ei ai se aafiaga bactericidal maualuga i pylori Helicobacter. Le faatamaia o siama i le taimi o le talosaga o lona uiga i le tuufaatasiga i fualaau faasaina aneti-siama ua tuuina atu faatasi ma se tulaga sagatonu aveesea vave uma auga, faapea foi ma se tulaga maualuga o le faamalologa o le mucosa aafia o le tamaitusi digestive. I le faaopoopo atu, o lenei faiga e uunaia ai le faamagaloina umi o faamaʻi ulcerative, lea e matuai faaitiitia ai le ono toto faifaipea.

Isi meatotino a le fualaau faasaina

O a isi meatotino maua lea ituaiga o sauniuniga o le "Losek CI"? faatonuina tagata tomai faapitoa Guest o gasegase oe aunoa ma mo se taimi umi, ia fualaau e taofia ai le secretion o le glands o le tamaitusi digestive, ua masani ona matauina cysts glandular i le manava. O se tulafono, o loo latou benign ma mou ese atu i latou lava.

Le tuuina i lalo o secretion acid hydrochloric i le manava uunaia microflora intestinal masani. Peitai, o lenei e mafai ona taitai atu ai i se faateleina laitiiti i le tulaga lamatia o le atiina ae pipisi.

I tagata matutua ma tamaiti, aveina se taimi umi o le tupe, o le siitia o le numera o sela enterochromaffin matauina.

Taimi o le togafitiga ma omeprazole faasalaga o gastrin i le toto matua faateleina.

Pharmacokinetics

E manatu faapito i le vailaau bloodstream "Losek CI"? Faatonuga mo le faaaogaina tautino mai mitiia o omeprazole tupu i totonu o le tamai suʻia (i totonu o le 4-6 itula). Talisuaga i le bioavailability o le mea e le o aafia. Ina ua mavae le pulega tuufofoga e tusa ma le 60%.

ua atoatoa metabolized le fualaau oona i le ate. O le afa o le olaga e uiga i le 30-80 minute. E tusa ma le 80% o le malosi mea ua excreted pei metabolites e le fatugaʻo, ma le vaega na totoe faatasi ma feces.

mau

Papa "Losek CI" ua faatonuina mo le sese faalemataupu nei:

• manava papala;
• esophagitis reflux;
• papala 12 papala duodenal;
• tafia o le suʻia e mafua mai i NSAIDs;
• le faatamaia o pylori Helicobacter;
• dyspepsia, lea e fesootai ma acidity maualuga;
• faamaʻi reflux gastroesophageal (symptomatic);
• syndrome Zollinger-Ellison.

Contraindications

Sauniuniga "Losek CI" e le mafai ona faatonuina mo le a hypersensitivity onosai e omeprazole faapea foi suia benzimidazoles po o isi vaega o vaega o le fualaau faasaina.

E tatau foi ona taʻua e faapea ua faatonuina lenei fualaau faasaina ma le faaeteete i luma o le tagata e foliga e pei o le fuafuaina leiloa mamafa, dysphagia, soo faasuati ma faasuati o le toto. Gata i lea, i papala gastric (po o ua masalomia faamai) e tatau ona aveesea le afioaga o le a patu matuia. ua mafua ona o le mea moni e faapea e faigofie lava ona togafitia ma omeprazole ufimata o le auga ma le faatuai i le vaaiga saʻo lenei.

E faapefea e le vailaau "Losek CI" (20 mg)?

O le tupe e tatau ona na ona faia tuufofoga i le taeao. O le fualaau e tatau ona faaumatia atoa i le vai. le tatau ona tuʻimomomoina po lamuina le fualaau faasaina.

O le fualaau ua faatagaina e faataapeina i teisi acid suavai po o le vai (f.t.t., i le sua fua). Ae peitai, o le taunuuga o le fofo e tatau ona faaumatia i totonu o se itula.

A esophageal reflux, gastric ma papala duodenal se 12-sauniuniga ua faatonuina 20 mg faatasi i le aso. A reflux esophagitis inumaga faateleina faalua.

Umi o le vaitaimi o togafitiga mo ulcers o le 2-4 vaiaso, ma reflux esophagitis - 4 vaiaso, ma gastroesophageal reflux - 4-8 vaiaso. Ina ia taofia relapses o ulcers ma e mafai ona tofia reflux oesophagitis a toe mauaina o le fualaau faasaina i se inumaga o le 10 mg.

itu aafiaga

Faafomai "Losek CI" analogs e mafai ona mafua ai fualaau faasaina aafiaga itu. Ua taatele nei tuutuuga pathological: ulu tiga, flatulence, tiga lona manava, manava masuasua, manavatatā, faafaufau ma faasuati.

Mo lē tāʻaga aafiaga itu aofia dermatitis, hives, dizziness, itching, paresthesia, mageso, malaise, drowsiness, gaoioiga faateleina o enzymes ate, ma moe fiti.

Nai seasea ona tupu i gasegase mauaina omeprazole tulai tali hypersensitivity (f.t.t., teʻi anaphylactic, fiva, anaphylaxis, edema angioneurotic), ma bronchospasm, hepatitis, maso vaivaiga, toilalo hepatic, leukopenia, encephalopathy, arthralgia, faanoanoa, myalgia, pancytopenia, thrombocytopenia, le le fiafia, agranulocytosis, gutu matutu, hyponatremia, candidiasis gastrointestinal, osoga, photosensitivity, fenumiai ma faaaliga faanenefu, manatu faatupu, afuafu tetele, tofo faalavelave, Periph edema -geometric, stomatitis, nephritis interstitial, alopecia, gynecomastia, erythema multiforme, microscopic colitis, Stevens-Johnson syndrome ma oona necrolysis epidermal.

Lava matauina seasea hypocalcemia, hypomagnesemia, hypokalemia ma hypomagnesemia.

Faafomai "Losek CI": tau ma analogues

Pe a faatusatusa i fualaau faasaina e tasi, o le tau o le tupe e fai lava si maualuga. O lea, mo le 14 papa o le ae maua e totogi ai e uiga i le 250 rubles Rusia. Mafaufau i le pulega mo se taimi umi o medicament (2 i le 8 vaiaso), e taugata tele le togafitiga mo i latou.

Le suitulaga mo le fualaau faasaina "Losek CI"? Analogs o le meafaigaluega ua i ai le le lelei e tasi. Ae peitai, i luma o le faaaogaina i latou, ia mautinoa e talanoa i lau fomaʻi.

O lea, sui ai le vailaau "Losek CI" Atonu o fualaau nei: "Omeprazole eka", "Vero omeprazole", "Tsisagast", "Gastrozol", "Helol", "Demeprazol", "Helitsid", "Zhelkizol", "Ultop "" Zerotsid "," Ulkozol "," Zolser "," Ulzol "," Krismel, "" O sopranos, "" Losek "," Romesek "," Omez "," Promez "," Omez MF "," Pleom- 20 "," Omez Insta "," Peptikum "," Omezol "," Otsid "," Omekaps "," Ortanol "," omeprazole "," Omitoks "," Omeprazole-Richter, "" Omipiks "," Omeprazole Stada " "Omizak", "Omeprazole Zentiva", "Omefez", "Sandoz Omeprazole", "Omeprus", "Omeprazole-OBL", "Omeprazole-FPO" "Omeprazol-Teva", "Omeprazole-Akos".

i molimau

O le a gasegase fai atu e uiga i le fualaau faasaina "Losek CI"? Faamatalaga e uiga i lenei nofoaga e matua lelei. E tusa ai ia i latou oe ua uma ona fai mai medicament, ua lava lelei aveesea auga uma o acidity o sua gastric. Ma o le taunuuga o le iloa e toetoe lava ina ua tuanai le taumafaina o fualaau (1-2 itula).

E masani ona iloiloina le auala e faaaoga mo manava tīgā ma se mu lagona i tua o le breastbone.

E ui lava i le lelei sili o le fualaau faasaina, o le tele gasegase faitio ina ua mavae le faamutaina toe foi o lona faaletonu le ulufale. I lenei tulaga, fomai pepa faataga e faia ai a faaaogaina atoatoa togafitiga ma vailaau e le itiiti ifo o le fa vaiaso.